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1

1H,13C, and15N resonance assignments for the small G protein RalB in its active conformation

Sunil Prasannan, R. Bryn Fenwick, Louise J. Campbell, Katrina A. Evetts, Daniel Nietlispach, Darerca Owen, Helen R. Mott

Journal:

Biomolecular NMR Assignments

Year:

2007

Language:

english

File:

PDF, 82 KB

english, 2007

2

10.1038/20739

Laue, Ernest D., Mott, Helen R., Owen, Darerca, Nietlispach, Daniel, Lowe, Peter N., Manser, Edward, Lim, Louis

Journal:

Year:

1999

Language:

english

File:

PDF, 448 KB

english, 1999

3

10.1038/20732

Laue, Ernest D., Mott, Helen R., Owen, Darerca, Nietlispach, Daniel, Lowe, Peter N., Manser, Edward, Lim, Louis

Journal:

Year:

1999

Language:

english

File:

PDF, 483 KB

english, 1999

4

Bioblockades join the assault on small G protein signalling

Mott, Helen R., Owen, Darerca

Journal:

Seminars in Cancer Biology

Year:

2018

Language:

english

File:

PDF, 1.43 MB

english, 2018

5

Control of p53 Expression by Adenovirus 12 Early Region 1A and Early Region 1B 54K Proteins

ROGER J.A. GRAND, DARERCA OWEN, SUSAN M. ROOKES, PHILLIP H. GALLIMORE

Journal:

Year:

1996

Language:

english

File:

PDF, 221 KB

english, 1996

6

Cdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover

Watson, Joanna R., Owen, Darerca, Mott, Helen R.

Journal:

Year:

2016

Language:

english

File:

PDF, 832 KB

english, 2016

7

Allostery and dynamics in small G proteins

Mott, Helen R., Owen, Darerca

Journal:

Biochemical Society Transactions

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

8

Specificity Determinants on Cdc42 for Binding Its Effector Protein ACK †

Elliot-Smith, Andrea E., Mott, Helen R., Lowe, Peter N., Laue, Ernest D., Owen, Darerca

Journal:

Year:

2005

Language:

english

File:

PDF, 498 KB

english, 2005

9

Double Mutant Cycle Thermodynamic Analysis of the Hydrophobic Cdc42−ACK Protein−Protein Interaction †

Elliot-Smith, Andrea E., Owen, Darerca, Mott, Helen R., Lowe, Peter N.

Journal:

Year:

2007

Language:

english

File:

PDF, 165 KB

english, 2007

10

1H,13C and15N resonance assignments of the Cdc42-binding domain of TOCA1

Watson, Joanna R., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.

Journal:

Biomolecular NMR Assignments

Year:

2016

Language:

english

File:

PDF, 651 KB

english, 2016

11

Bond swapping from a charge cloud allows flexible coordination of upstream signals through WASP: Multiple regulatory roles for the WASP basic region

Tetley, George J. N., Szeto, Aydan, Fountain, Adam J., Mott, Helen R., Owen, Darerca

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 3.33 MB

english, 2018

12

Mutational Analysis Reveals a Single Binding Interface between RhoA and Its Effector, PRK1

Hutchinson, Catherine L., Lowe, Peter N., McLaughlin, Stephen H., Mott, Helen R., Owen, Darerca

Journal:

Year:

2011

Language:

english

File:

PDF, 3.33 MB

english, 2011

13

1H, 15N and 13C resonance assignments of the HR1c domain of PRK1, a protein kinase C-related kinase

Sophocleous, Georgios, Wood, George, Owen, Darerca, Mott, Helen R.

Journal:

Biomolecular NMR Assignments

Year:

2020

File:

PDF, 1.05 MB

2020

14

10.1038/40202

Laue, Ernest D., Luh, Frederich Y., Archer, Sharon J., Domaille, Peter J., Smith, Brian O., Owen, Darerca, Brotherton, Deborah H., Raine, Andrew R. C., Xu, Xu, Brizuela, Leonardo, Brenner, Stephen L.

Journal:

Year:

1997

Language:

english

File:

PDF, 693 KB

english, 1997

15

10.1038/40208

Laue, Ernest D., Luh, Frederich Y., Archer, Sharon J., Domaille, Peter J., Smith, Brian O., Owen, Darerca, Brotherton, Deborah H., Raine, Andrew R. C., Xu, Xu, Brizuela, Leonardo, Brenner, Stephen L.

Journal:

Year:

1997

Language:

english

File:

PDF, 37 KB

english, 1997

16

A Novel Protein Expressed in Mammalian Cells Undergoing Apoptosis

Roger J.A. Grand, Anne E. Milner, Tracey Mustoe, Gerald D. Johnson, Darerca Owen, Michael L. Grant, Christopher D. Gregory

Journal:

Experimental Cell Research

Year:

1995

File:

PDF, 1.32 MB

1995

17

Differential Binding of RhoA, RhoB, and RhoC to Protein Kinase C-Related Kinase (PRK) Isoforms PRK1, PRK2, and PRK3: PRKs Have the Highest Affinity for RhoB

Hutchinson, Catherine L., Lowe, Peter N., McLaughlin, Stephen H., Mott, Helen R., Owen, Darerca

Journal:

Year:

2013

Language:

english

File:

PDF, 6.56 MB

english, 2013

18

Erratum to:1H,13C and15N resonance assignments of the Cdc42-binding domain of TOCA1

Watson, Joanna R., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.

Journal:

Biomolecular NMR Assignments

Year:

2016

Language:

english

File:

PDF, 452 KB

english, 2016

19

DNA sequence analysis of the imp UV protection and mutation operon of the plasmid TP110: identification of a third gene

Lodwick, David, Owen, Darerca, Strike, Peter

Journal:

Nucleic Acids Research

Year:

1990

Language:

english

File:

PDF, 4.12 MB

english, 1990

20

Structures of Ras superfamily effector complexes: What have we learnt in two decades?

Mott, Helen R., Owen, Darerca

Journal:

Critical Reviews in Biochemistry and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 4.47 MB

english, 2015

21

Structure and function of RLIP76 (RalBP1): an intersection point between Ras and Rho signalling

Mott, Helen R., Owen, Darerca

Journal:

Biochemical Society Transactions

Year:

2014

Language:

english

File:

PDF, 651 KB

english, 2014

22

Peptide mimetics of nucleotide phosphate binding sites

Keane, Noeleen E., Molloy, David P., Grand, Roger J. A., Owen, Darerca, Levine, Barry A., Ellis, Leland

Journal:

Biochemical Society Transactions

Year:

1993

Language:

english

File:

PDF, 90 KB

english, 1993

23

Solution Structure and Dynamics of the Small GTPase RalB in Its Active Conformation: Significance for Effector Protein Binding †‡

Fenwick, R. Bryn, Prasannan, Sunil, Campbell, Louise J., Nietlispach, Daniel, Evetts, Katrina A., Camonis, Jacques, Mott, Helen R., Owen, Darerca

Journal:

Year:

2009

Language:

english

File:

PDF, 7.01 MB

english, 2009

24

1H,13C and15N resonance assignments for Binder of Arl2, BART

Laura K. Bailey, Louise J. Campbell, Katrina A. Evetts, Keily Littlefield, Eeson Rajendra, Daniel Nietlispach, Darerca Owen, Helen R. Mott

Journal:

Biomolecular NMR Assignments

Year:

2009

Language:

english

File:

PDF, 301 KB

english, 2009

25

The High Levels of p53 Present in Adenovirus Early Region 1-Transformed Human Cells do Not Cause Up-Regulation of MDM2 Expression

Roger J.A. Grand, Philip S. Lecane, Darerca Owen, Michael L. Grant, Sally Roberts, Arnold J. Levine, Phillip H. Gallimore

Journal:

Year:

1995

File:

PDF, 919 KB

1995

26

1H,13C and15N resonance assignments of the GTPase-activating (GAP) and Ral binding domains (GBD) of RLIP76 (RalBP1)

Rajasekar, Karthik V., Campbell, Louise J., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.

Journal:

Biomolecular NMR Assignments

Year:

2012

Language:

english

File:

PDF, 681 KB

english, 2012

27

Thermodynamic Mapping of Effector Protein Interfaces with RalA and RalB

Campbell, Louise J., Peppa, Maria, Crabtree, Michael D., Shafiq, Arooj, McGough, Nicholas F., Mott, Helen R., Owen, Darerca

Journal:

Year:

2015

Language:

english

File:

PDF, 6.34 MB

english, 2015

28

CRIB effector disorder: exquisite function from chaos

Owen, Darerca, Mott, Helen R.

Journal:

Biochemical Society Transactions

Year:

2018

Language:

english

File:

PDF, 5.02 MB

english, 2018

29

Structural Analysis of the SH3 Domain of β-PIX and Its Interaction with α-p21 Activated Kinase (PAK) †,‡

Mott, Helen R., Nietlispach, Daniel, Evetts, Katrina A., Owen, Darerca

Journal:

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

30

Inhibition of Ral GTPases Using a Stapled Peptide Approach

Thomas, Jemima C., Cooper, Jonathan M., Clayton, Natasha S., Wang, Chensu, White, Michael A., Abell, Chris, Owen, Darerca, Mott, Helen R.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

31

10.1038/20741

Laue, Ernest D., Mott, Helen R., Owen, Darerca, Nietlispach, Daniel, Lowe, Peter N., Manser, Edward, Lim, Louis

Journal:

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

32

Ras binding to a C-terminal region of GAP

David P. Molloy, Darerca Owen, Roger J.A. Grand

Journal:

Year:

1995

Language:

english

File:

PDF, 745 KB

english, 1995

33

A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK

Tetley, George J. N., Mott, Helen R, Cooley, R. Neil, Owen, Darerca

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 2.77 MB

english, 2017

34

1H,13C, and15N resonance assignments for the small G protein RalB in its active conformation

Sunil Prasannan, R. Bryn Fenwick, Louise J. Campbell, Katrina A. Evetts, Daniel Nietlispach, Darerca Owen, Helen R. Mott

Journal:

Biomolecular NMR Assignments

Year:

2007

Language:

english

File:

PDF, 227 KB

english, 2007

35

1H,13C and15N resonance assignments for the active conformation of the small G protein RalB in complex with its effector RLIP76

R. Bryn Fenwick, Sunil Prasannan, Louise J. Campbell, Katrina A. Evetts, Daniel Nietlispach, Darerca Owen, Helen R. Mott

Journal:

Biomolecular NMR Assignments

Year:

2008

Language:

english

File:

PDF, 434 KB

english, 2008

36

Therapeutic peptides targeting the Ras superfamily

Hurd, Catherine A., Mott, Helen R., Owen, Darerca

Journal:

Peptide Science

Year:

2020

File:

PDF, 3.11 MB

2020

37

Delineation of the Cdc42/Rac-Binding Domain of p21-Activated Kinase

Thompson, Gladstone, Owen, Darerca, Chalk, Peter A., Lowe, Peter N.

Journal:

Year:

1998

Language:

english

File:

PDF, 86 KB

english, 1998

38

Resonance assignments for the RLIP76 Ral binding domain in its free form and in complex with the small G protein RalB

R. Bryn Fenwick, Sunil Prasannan, Louise J. Campbell, Katrina A. Evetts, Daniel Nietlispach, Darerca Owen, Helen R. Mott

Journal:

Biomolecular NMR Assignments

Year:

2008

Language:

english

File:

PDF, 355 KB

english, 2008

39

The RalB-RLIP76 Complex Reveals a Novel Mode of Ral-Effector Interaction

R. Brynmor Fenwick, Louise J. Campbell, Karthik Rajasekar, Sunil Prasannan, Daniel Nietlispach, Jacques Camonis, Darerca Owen, Helen R. Mott

Journal:

Year:

2010

Language:

english

File:

PDF, 1.30 MB

english, 2010

40

The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane

Rajasekar, Karthik V., Campbell, Louise J., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.05 MB

english, 2013

41

Investigation of the Interaction between Cdc42 and Its Effector TOCA1

Watson, Joanna R., Fox, Helen M., Nietlispach, Daniel, Gallop, Jennifer L., Owen, Darerca, Mott, Helen R.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 3.78 MB

english, 2016

42

NMR resonance assignments for the active and inactive conformations of the small G protein RalA

Shafiq, Arooj, Campbell, Louise J., Owen, Darerca, Mott, Helen R.

Journal:

Biomolecular NMR Assignments

Year:

2020

File:

PDF, 827 KB

2020

43

RLIP76 (RalBP1)

Mott, Helen R., Owen, Darerca

Journal:

Year:

2010

Language:

english

File:

PDF, 1002 KB

english, 2010

44

The discovery and maturation of peptide biologics targeting the small G protein Cdc42: a bioblockade for Ras-driven signalling

Tetley, George J. N., Murphy, Natasha P., Bonetto, Stephane, Ivanova-Berndt, Gabriela, Revell, Jefferson, Mott, Helen R, Cooley, R. Neil, Owen, Darerca

Journal:

Journal of Biological Chemistry

Year:

2020

Language:

english

File:

PDF, 7.30 MB

english, 2020

45

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

Hurd, Catherine A, Brear, Paul, Revell, Jefferson, Ross, Sarah, Mott, Helen R, Owen, Darerca

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 3.66 MB

2020

46

Residues in Cdc42 That Specify Binding to Individual CRIB Effector Proteins

Owen, Darerca, Mott, Helen R., Laue, Ernest D., Lowe, Peter N.

Journal:

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

47

10.1038/75158

Laue, Ernest D., Morreale, Angela, Venkatesan, Meenakshi, Mott, Helen R., Owen, Darerca, Nietlispach, Daniel, Lowe, Peter N.

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 455 KB

english, 2000

48

10.1038/41805

Gamblin, Steven J., Rittinger, Katrin, Walker, Philip A., Eccleston, John F., Nurmahomed, Kurshid, Owen, Darerca, Laue, Ernest, Smerdon, Stephen J.

Journal:

Year:

1997

Language:

english

File:

PDF, 629 KB

english, 1997

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